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FRONTLINE Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 3 Treatments

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$39.98

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About this item

Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus

4.4 out of 5 stars Date First Available May 30, 2004 Item Package Dimensions L x W x H 5.87 x 4.37 x 0.75 inches Item Dimensions LxWxH 5.75 x 0.75 x 4.5 inches Item Weight 1.6 Ounces Brand Name Frontline Target Audience Keyword dogs Directions Directions for Use Step 1. To REMOVE Applicator: 1. Use scissors to separate one blister; 2. Use scissors to cut along dotted line; 3. Peel down foil to remove the applicator. Step 2. OPEN Applicator. Hold upright with foil side toward you and snap applicator tip. Step 3. APPLY FRONTLINE Plus. Part the dog’s hair between the shoulder blades. Place the applicator tip just above the skin and squeeze. Apply entire contents of the applicator in a single spot directly onto the dog’s skin. Do not apply on top of the hair coat. Avoid contact with treated area until dry. Do not allow your dog to ingest the product. Do not apply to dogs weighing less than 89 lbs. or younger than 8 weeks of age. Do not use more than one application per dog per month. Frequency Use monthly to control fleas and ticks. Do not reapply FRONTLINE Plus for 30 days. Country of Origin France Warranty Description If you are not satisfied with FRONTLINE Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842 Model Name FRONTLINE Plus Extra Large Dog Color Red Box Size 3 Count Age Range Description All Life Stages Number of Items 3 Manufacturer Boehringer Ingelheim Animal Health Style 3 Count Breed Recommendation Large Breeds Included Components Package includes 3 applicators Specific Uses for Product Parasites

Product Description

Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention.

Brand Story

By Frontline Plus

Missy88087

Reviewed in the United States on March 8, 2025

Works great and good price

Jahdani

Reviewed in the United States on March 2, 2025

This works wonders for my dogs! Have been using the Frontline product line for my dogs for years now and so trust me when I say it works within days.

rrp

Reviewed in the United States on February 27, 2025

Cancelled using. Too expensive.

Linda Austin

Reviewed in the United States on January 24, 2025

This product didn't seem to work for me as well as it did in the past. Did not keep the fleas off as well as before and he was still itching and scratching. I think I would like to try something else in the spring.

Susan the Grouch

Reviewed in the United States on September 23, 2024

Easy to apply if you can make a part in your dog's hair.I always get it on my hands and wash it off as soon as I am done with the dogs. Never a problem on my skin due to this timeliness I guess.Kills the ticks who settle down to bite and still works on fleas for me. Ten miles down the road, however, it does not work anymore. Life finds away...

donna box

Reviewed in the United States on September 15, 2024

Easy to use does it make my dog's feel bad a lot of that medication makes them sickly.

Kimberly Zittlow

Reviewed in the United States on November 22, 2024

As the proud owner of two large dogs, keeping them flea- and tick-free is a priority, especially since we live in an area where these pests are a constant concern. Frontline Plus for Dogs has been my go-to solution for years, and it continues to deliver the protection my dogs need.What I love most about this product is its consistent effectiveness. Both of my dogs, a Blue Heeler and a Labrador mix, weigh over 90 pounds, and this X-Large size is perfect for their needs. After applying Frontline Plus, I notice a visible difference within a day or two—no scratching, no signs of fleas or ticks, and a much happier pup!Applying the treatment is straightforward. I part their fur, place the applicator tip on their skin, and squeeze. It's quick, mess-free, and easy to include in my monthly routine. One of my dogs is prone to skin sensitivities, and I’m happy to report that Frontline doesn’t irritate his skin at all, which is a big relief for me as a pet parent.I also appreciate the added protection against flea eggs and larvae, not just the adult fleas. This has been a game-changer, especially during peak flea season. Knowing it targets the full flea life cycle gives me peace of mind that my dogs are fully protected.One tip: Be consistent with the application schedule. I’ve learned that sticking to a monthly routine ensures there’s no gap in protection. Even if we miss a dose by a few days, Frontline still works great, but keeping up with the timeline keeps my dogs at their happiest and healthiest.Frontline Plus is worth every penny for the reassurance it provides. Whether your dogs are always outside exploring or just lounging in the yard, this product has proven itself time and time again. Highly recommend it to all pet parents who want effective, dependable flea and tick control!

KittyResQ

Reviewed in the United States on October 2, 2019

I generally try to keep flea spot-on around because I do cat rescue. Before anyone declares - "Wait this is for DOGS, not cats!!!" I AM working with a VET that tells me the exact amount to give based on weight. I have a scale & needless syringe. This is the same product just packaged & weighed differently. It's all good.Anyways, getting the poor babies off the street, most of the time they are covered with fleas (& eat mites). When I ordered this I was switching brands because it seemed like the other brand just wasn't working as well any longer. I thought that if I used something different it would help. Boy was I wrong.The fleas are worse than ever now. Despite dosing every 2 weeks! (Again - VET advice) It just reminds me of why I stopped using Frontline in the first place.... It didn't work. I might as well have flushed my money down the toilet. If used as a PREVENTATIVE every month then I think this would be fine. But if you find yourself in the midst of a flea invasion of epic proportions. (3 new cars brought in and within a month, despite keeping them separatex, all 6 of my cats & my dog were covered in fleas. And that was AFTER using this on everyone as soon as the 1st cat was rescued.)So if you are going to use this monthly without fail then you should be fine. But if you suddenly notice a few fleas on your pet then prepare for battle! Great your animals, your house, and your yard. Then keep repeating this cycle. Make sure you vacuum and empty the vacuum cleaning outside. I highly recommend using diatomaceous earth on your carpets/rugs. I even put it on the animals to help them. You can also give them Nitenpyram (CapStar), which acts almost instantly and can be given to them every 2 days. Like I said....prepare for war.This Frontline has NOT helped in my situation. The animals didn't even have one day of relief. The dog is tearing herself apart even more now than she did prior to her treatment. I think water would've given me the same results and cost less.