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Your cart is empty.4.3 out of 5 stars
"Cat lovers choose Advantage XD for double the lasting protection against fleas vs. other 1-month options. Advantage XD for large cats and kittens packs two full months of treatment and continuous protection in each dose, so your cat is protected for longer than the traditional 1-month formula.* If your cat has already tousled with fleas, you’ll love that Advantage XD topical treatment starts killing fleas within 30 minutes to 4 hours through contact so they don’t have to bite and die. And with Advantage XD extended duration formula, that flea prevention remains effective for 8 weeks, outlasting the typical 6-week flea life cycle and preventing reinfestation.
Find Advantage XD topical flea treatment available in a variety of pack sizes, from 2 months protection (1 dose), to 4 months protection (2 doses), or 8 months protection (4 doses). This fragrance-free formula contains Spinetoram, a naturally derived, Green Chemistry Award-winning** ingredient.
Advantage XD flea infestation prevention is effective on both indoor and outdoor cats. Your cat should be at least 8 weeks old and weigh over 9 lbs. to use Advantage XD for large cats. Even with the squirmiest of kittens and cats, application is easy. The single, topical, spot-on application goes on the back of your cat’s neck at the base of the skull. You’ll simply place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. It's easier, there are no hard-to-swallow pills; this topical treatment goes on in seconds. See product label for more information.
For the ultimate convenience in care, Advantage XD is available over the counter – no prescription needed. Once Advantage XD is applied, your cat is ready to get right back to exploring the outdoors or finding a cozy spot for a nap, while you get to enjoy peace of mind.
*Based on label claims **US EPA Presidential Green Chemistry Challenge. Designing Greener Chemicals Award. 2008. "
FishinQueen
Reviewed in the United States on March 6, 2025
Good flea control. And easy to put on cat.
Lawrence Trotta III
Reviewed in the United States on February 8, 2025
I was having a hard time finding flea meds to use. Our indoor cats have not had issues for YEARS. But some rogue fleas blew up and we had to knock them out. We put these on everyone and gave a capstar and it worked like a charm. Best I’ve used in awhile. Opening them took some getting used to but I may just be dumb so read the directions or risk it all over your hands. Not had an issue since.
Bill B
Reviewed in the United States on February 22, 2025
Easy to use .Cat had no ill effects and it looks like what was there is now gone
Lisa c j aka Lisa Johnson
Reviewed in the United States on February 20, 2025
Will never use this product on my cat again!! Burnt the back of his neck. Hurt so badly that he ripped his hair out in the back of his neck!! It was awful and I felt horrible.
chri sweeney
Reviewed in the United States on February 13, 2025
Applied this to my 3 cats about 4 days ago and it appears to have worked! No signs of live fleas on the short haired ones anymore and no side effects to speak of which is great because I was worried about skin irritation from trying a new product.It was easy enough to apply once I realized you didn't have to take the cap completely off and I'm pleased that you only have to apply it once every two months as I am forgetful.My only complaint is that it has been four days and my long haired cat (pictured) still has funky gunky residue on their fur. I applied it at the base of their skull per the instructions and the goo seems to have settled into their hair and is now collecting dust. This is less worrisome for me as my cats don't groom each other but if you have bonded cats this may be a problem as you don't want them ingesting the product. Cleaning it off of my cats neck will also be an issue because washing a cat is a perilous task.
Paige
Reviewed in the United States on January 12, 2025
I used it on two cats and in both cases, it didn't fully take care of the fleas. Although they were mostly reduced- I'd say 75% less fleas, I'll be going to go back to Advantage II. Although not fully effective, the XD still takes longer to wear off, so the cats have had to wait an extra month before it's safe to give them any other treatment. That bums us all out.
Vannessa Fongemie
Reviewed in the United States on November 25, 2024
This works a lot better on my cats then the traditional 4 weeks one. I noticed it does seem to last about 2 months! It's definitely worth the money I spent. Flea control has been excellent so far. Also it works about the same speed as the regular flea topical.I haven't noticed any side effects but pleas make sure your kitties don't lick the treatment.
CELTIC QUEEN
Reviewed in the United States on October 17, 2023
Caution!!! Don’t buy this product!!!!!We usually get a subscription from the vet during flea season, just in case. Our indoor cat hasn’t really needed it, up until now. Mochi somehow got fleas?!!! Unfortunately the subscription ihss expired.Mochi would scratch every once in a while, but we noticed it was a bit more than a usual itch or scratch to get to certain spot. So, we decided we will get an Advantage brand flea treatment (non/prescript) because we had pre-used a(different type) Advantage in the past and it worked pretty good,and it’s better to use it than nothing at all at least until we can go to vet.We purchased Advantage XO which was an advanced/improved version of previous product I had bought but, with an treatment extended for 2 months use in just in one dose.. save money sounds great,, and after reading reviews the customers had claimed that this product worked well. So we ordered it.We applied Advantage XO to our cat- hoping he will have some relief, and control the fleas.In just minutes after applying on the back of our cats neck, he started itching & scratching even more. he would walk and suddenly he was falling/ plopping himself down quickly on floor in order to scratch/bite where the fleas were. He was making a noise as if sucking/chewing on his skin to be rid of his discomfort. I have never heard him do that and made me keep an eye on him. It made me feel a bit worried. We had thought okay the fleas must be scattering/freaking out- so it must be working. My cat had a hard time that night scratching more than ever. I felt sorry for him.The next day it seemed like maybe it was slowing down he wasn’t scratching like previous day. I thought wrong he started scratching not as crazy but consistent. In the end it seemed to make the fleas worse if possible I don’t know?! But I do know I will never buy this again. I don’t want my cat to suffer or see what I did as a reaction to this flea treatment. I wasted my money, and in the end, I didn’t help him to feel better. Decided to go to the vet, much safer.
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