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Advantage II Large Dog Vet-Recommended Flea Treatment & Prevention | Dogs 21-55 lbs. | 4-Month Supply

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$50.98

$ 26 .99 $26.99

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1.Size:4-pack


About this item

  • Vet recommended flea treatment and prevention for dogs at weighing 21 to 55 lbs., at least 7 weeks of age
  • Kills adult fleas, flea larvae and flea eggs for total flea prevention and treatment
  • Same-day effectiveness, kills fleas within 12 hours of application and keeps working for 30 days
  • Easy-to-apply topical treatment, no prescription needed
  • Fragrance-free formula, waterproof after 24 hours



4.5 out of 5 stars Date First Available March 5, 2011 Item Package Dimensions L x W x H 4.72 x 4.37 x 1.46 inches Item Dimensions LxWxH 6.5 x 1 x 4.25 inches Item Weight 0.04 Pounds Brand Name Advantage Target Audience Keyword Dogs Directions Application Instructions: 1. Use only on dogs. 2. Hold applicator tube in an upright position. Pull cap off tube. 3. Turn the cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. 4. Apply the entire contents of the tube evenly to three or four spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. 5. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. 6. Do not apply an excessive amount of solution at any one spot that could cause the solution to run off the side of the dog. 7. Do not get this product in your dog’s eyes or allow them to ingest. Country of Origin Germany Model Name Advantage II Color Blacks & Grays Size 4-Pack Age Range Description 7 weeks and older Care Instructions Topical Treatment Number of Items 4 Manufacturer Elanco US Inc Style 4 doses Breed Recommendation Large Specific Uses for Product Parasites

Product Description

Advantage II Large Dog is the vet-recommended prevention and treatment of flea and lice infestations in dogs. Advantage II Large Dog flea treatment and prevention kills adult fleas, flea larvae and flea eggs to deliver total flea protection to your dog or puppy. In fact, within 12 hours of application, Advantage II Large Dog topical treatment gets straight to work killing fleas through contact, so they don’t have to bite your dog to die.

This 30-day treatment effectively breaks the flea life cycle, controlling existing flea and lice infestations and preventing further infestations all month long. Fleas not only cause discomfort; they can also pose other health risks. Monthly use of Advantage II Large Dog is important to protect your dog against fleas that may cause transmission of tapeworms in dogs, Flea Allergy Dermatitis and flea bite anemia.

That’s why Advantage II topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that Advantage II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects.

Advantage II Large Dog flea and lice protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh 21 to 55 lbs. to use Advantage II Large Dog.

For the ultimate convenience in care, Advantage II Large Dog is available over the counter – no prescription needed. And, you can stock up with a subscription for regular doorstep deliveries so you never miss a monthly treatment. Once Advantage II Large Dog is applied, your dog is ready to get right back to exploring his favorite places – from the backyard to the dog park.

Advantage II Large Dog is a trademark of Elanco or its affiliates.

Brand Story

By Advantage


wendy de la cruz
Reviewed in the United States on January 27, 2025
Works super well i used it once and my dog's fleas were finally gone life saver
Julie Dixon
Reviewed in the United States on August 30, 2024
Working great! I have not seen any fleas or ticks and they DO NOT scratch ever! Definitely will buy again
Jason
Reviewed in the United States on May 8, 2024
I only get Advantage 2 aa it works the best in my experience. My 3 year old fawn colored female American Pitbull Terrier started whining & itching so I checked her and she had fleas. Within a few days of putting this on my girl all her fleas are gone and haven't came back. It's so easy to use and has durability as it won't wash off. It doesn't smell bad and there are no bad side effects. I highly recommend it and make sure you get it from Amazon because it's so much cheaper. It's almost twice the price at petsmart and petco!
Tonya Dean
Reviewed in the United States on May 23, 2024
It took us several years to finally get a flea product that actually worked as advertised. This is it folks. Save yourself the trouble and aggravation of trying to find a flea product for your dog that actually works. This is the one! Granted, it's not cheap but it works to continually kill fleas and their eggs so your dog(s) won't be scratching, and your house will stay free of fleas! Do yourself and your pets a favor and purchase this Advantage II Flea Treatment and Prevention product! Nothing works as well!
Ellie Hutmire
Reviewed in the United States on December 18, 2024
Within 24 hours of application, all the fleas were gone!
pelly
Reviewed in the United States on October 29, 2024
I have a husky sheep dog mix, and although this was recommended by my vet, I don't think it's made for dogs with very thick fluffy hair. This is the second month ive used it and he continues to itch. This never used to happen with the edible, unfortunately it was very difficult to get him to eat these, because apparently they taste like s*** so I decided to try the topical. now he's going to continue to scratch for the rest of the month and be miserable, and there's nothing I can do about it. Seems to work fine on my other dog, who is a wire hair mix.
chacowalla
Reviewed in the United States on July 5, 2017
I've used advantage II for years and get it from Amazon at a much better price that from the vets. But it seems to not be doing a good a job that it has in the past. I just got a new box of 6 and will see. I don't know what I will get to replace it if it has stopped working, so will keep my fingers crossed that maybe I just got a weak batch. There is no expiration date on any of the boxes, just a code, and the manufacturer won't give you the date in normal month/year format because they are not required to by law. Also, the box I just received today was opened, and the side fold at the top was ripped (not by me) but of course, the individual tubes are sealed up in mylar so I don't worry they have been tampered with, but that it was unusual. All in all a good product, but I am watching it!
Travis
Reviewed in the United States on January 9, 2016
I know there are A-LOT of bad reviews for these but my belief is that people are using the product wrong, possibly issuing wrong doses or ordering the wrong product size. Bayer is a local, well known, trusted company in my area and I can tell you that they do not manufacture products that would kill your animals or harm them. This is a local, USA company. I have had family members that have worked for them their entire lives.Now on to the product. It works very well. We were using Frontline but it did not work. AT ALL. Our dog was getting ticks, our cats and dog had fleas. We used Frontline religiously and it just didn't perform. We ended up with a really bad flea infestation in our home and we needed to take action as multiple flea baths and house treatment were not helping. We finally switched to advantage II. Weary about the reviews we applied it to our animals in the proper dosage, size, and areas. Read, read and re-read the instructions. There are specific ways to apply this for specific animals. There are also specific sizes that you purchase depending on the type and weight of your animal. YOU NEED TO READ! Within two weeks after we treated our house with products known as permethrin and I.G. regulators as well as using Bayer Advantage II we completely got rid of our flea problem. Its now been months since we have had the problem and we haven't found a single flea on our animals. This stuff just hands down works. I would recommend to anybody and I'm going to keep purchasing it because I never want to have fleas in my home again. Its well worth the price.UPDATE: Its now been 5 years since my original review and we still use this. We have not had a single flea issue since my original review. Our animals are safe and healthy. Be aware that there are counterfeits on Amazon. There are articles on the internet of what to check for. If you are concerned, purchase it from your vet or Chewy.
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